An Enzymatic Deantigenation Process Allows Achieving Physiological Remodeling and Even Osteopromoting Bone Grafting Materials
نویسندگان
چکیده
منابع مشابه
Physiological bases of bone regeneration II. The remodeling process.
Bone remodeling is the restructuring process of existing bone, which is in constant resorption and formation. Under normal conditions, this balanced process allows the renewal of 5-10% of bone volume per year. At the microscopic level, bone remodeling is produced in basic multicellular units, where osteoclasts resorb a certain quantity of bone and osteoblasts form the osteoid matrix and mineral...
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Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone mass and systemic mineral homeostasis. This review highlights recent work on physiological bone remodeling and discusses our knowledge of how systemic and growth factors regulate this process.
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Bone adaptation occurs as a response to external loadings and involves bone resorption by osteoclasts followed by the formation of new bone by osteoblasts. It is directly triggered by the transduction phase by osteocytes embedded within the bone matrix. The bone remodeling process is governed by the interactions between osteoblasts and osteoclasts through the expression of several autocrine and...
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ژورنال
عنوان ژورنال: Biotechnology & Biotechnological Equipment
سال: 2007
ISSN: 1310-2818,1314-3530
DOI: 10.1080/13102818.2007.10817500